A comparative study of 8-epi-prostaglandin f2 alpha , selenium levels in preterm , term Iraqi infants and their mothers

الملخص

Abstract Free radical injury is thought to be one of the common mechanisms for several diseases in preterm infants. Lipid peroxidation plays a vital role in the pathogenesis of many neonatal complications because the antioxidant system of preterm infants is highly stressed and incompletely developed. The aim of study is determination of the oxidative stress [8-epi-prostaglandin F2alpha [(8-epi-PGF2α)] and nutrient antioxidants [Selenium (Se)] in cord blood of preterm (n=31), term LBW infants (n=27) , term NBW infants (30) and in the blood of their mothers .In preterm infants & their mothers Selenium levels were low as compared to term infants and their mothers. In preterm infants & their mothers 8-epi-prostaglandin F2alpha were high as compared to term infants and their mothers. Therefore it is possible to postulate that preterm infants and their mothers are more susceptible to oxidative stress than term infants and their mothers.