Cytomegalovirus (CMV) is the prototype member of Betaherpesvirinae in the subfamily Herpesviridae.
CMV is endemic in most areas of the world. The sero-prevalence of HCMV varies in different geographical areas and it ranges from 30-100%. The infection of this virus is acquired either in the perinatal period and infancy or in adulthood through sexual contact, organ transplantation or blood transfusion. HCMV, like other herpesviruses, gives lasting settlement of the organism and its reservoir are mainly monocytes and polymorphonuclear leukocytes, where the virus is shed, many years after the initial infection (present in the throat and urine). The result of infection is seen basically in larger cells, and the presence of characteristic intracellular inclusions surrounded by halo of low reflection, gives the appearance of the so-called ‘Owl-eyes’. The virus gets into the salivary gland, breast epithelium, prostate, endometrium, kidney tubules, and other organs, such as bone marrow and lungs.
This review will shed light on sero-prevalence of HCMV in Iraq.
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March 02, 2018
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