This study showed that the Zirconium Oxide (ZiO2) nanoparticles have antifungal and antibacterial activities on the isolates of Cryptococcus neoformans, Candida albicans and Staphylococcus aureus, respectively. While the antimicrobial activity of Zirconium Oxide nanoparticles on the other fungi and bacteria such as Catumum and Pseudomonas aeruginosa was negative.
Detection of active compounds in the Trigonella foenum seed extract showed that Alkaloids, Flavonoids, Tannina and poly phenols were positive while Glycosides, Fatty acid, Terpenst and Steroid were negative, all tested fungi and bacteria isolates were found to be sensitive to Trigonella foenum seed extract.
The results of the combination of the ZiO2 Nanoparticle and the Trigonella foenum seed extract were positive for all tested fungi isolates (Cryptococcus neoformans, Candida albicans and Catumum) and bacteria isolates(Pseudomonas aeruginosa and Staphylococcus aureus).
The XRD analysis was done for Zirconium Oxide nanoparticles and the result showed that the biocrystallization on the surface of the Zirconium Oxide nanoparticles. The average particles size was about (29.8) nm.
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