ABSTRACT Introduction: Measuring biomarkers like kisspeptin and activins might provide prognostic and diagnostic clues for early pregnancy loss and other diseases. Some of these biomarkers’ increased or decreased values must be seriously considered, especially during pregnancy. Objective: This study aims to identify the micro-organisms causing surgical site infection and their susceptibility patterns towards the common antibiotics in surgical words at Al-Nu’man Teaching Hospital. Methods: A total of 90 women aged 18 and 40 years, less than 12 gestational weeks, were included in this case control study. Forty-six healthy pregnant women and 44 patients with early pregnancy loss (missed abortion) from the Gynecology and Obstetrics wards of the Al-Imamein A-lKadhimein Medical City between January 2022 and June 2022. Results: The mean serum level of kisspeptin in early pregnancy loss is 2.4±0.88 ng/ml, much lower than that in healthy pregnant women (4.21±1.33 ng/ml) with a highly significant difference. Likewise, healthy women had a higher level of activin A (766.77±299.13 pg/ml) than women with early pregnancy loss (331.16±62.39 pg/ ml) with a highly significant difference. In contrast, women with early pregnancy loss showed a higher level of activin AB than controls (378.82±98.72 pg/ml vs. 244.35±99.6 pg/ml) with a highly significant difference. There is a significant positive correlation between kisspeptin and the menstrual cycle duration (r=0.368, p= 0.018). Conclusion: Kisspeptin, Activins A, and Activin AB may be utilized as promising prognostic biomarkers for women with early pregnancy loss. Key words: Kisspeptin, activin A, Activin AB, miscarriage, biochemical pregnancies.
(FULL ARTICLE LINK) Read more ...
July 2024
|
|
|
