Doctoral Dissertation Explores the Role of Oxidative Stress Biomarkers in Diabetic Cardiovascular Complications

“Assessment of Methylglyoxal, Soluble Receptor for Advanced Glycation End-Products, and Malondialdehyde in Pre-Diabetic and Type 2 Diabetes Mellitus Patients in Relation with Cardiovascular Risk.”

The study aimed to evaluate the serum levels of:

in pre-diabetic patients and type 2 diabetes mellitus patients, and to investigate their association with cardiovascular risk, with the objective of exploring their potential role as biomarkers of oxidative stress related to these conditions.

The study revealed a significant elevation in MG, sRAGE, and MDA levels among type 2 diabetes mellitus patients, both with and without cardiovascular risk, compared to the pre-diabetic group and the control group. These biomarkers were higher in patients at risk of cardiovascular disease.

The Discussion Committee:

The dissertation was successfully accepted with a grade of Excellent.

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College of Medicine – Al-Nahrain University