The First Study in Iraq to Investigate the Association Between Genetic Variations and Type 2 Diabetes Markers

“Evaluation of Plasma Decoy Receptor 3, Phospholipid Transfer Protein Concentration, and Single Nucleotide Polymorphism of ATP Binding Cassette Transporter A1 in Pre-Diabetes and Newly Diagnosed Type 2 Diabetes Mellitus.”

The research further sought to explore the possible association between these biomarkers and certain clinical and metabolic features in the early stages of glucose dysregulation. It investigated whether single or combined point mutations in the ABCA1 gene sequence could contribute to the onset of type 2 diabetes by affecting lipid metabolism pathways, insulin signaling, and the efficiency of pancreatic insulin-producing beta cells. These parameters were selected due to their potential link with the initiation and progression of the disease, providing a deeper understanding of the genetic and molecular pathways that may predispose individuals to diabetes.

The discussion committee consisted of:

The dissertation was successfully accepted with a grade of Excellent.

Division of Media and Government Communication
College of Medicine – Al-Nahrain University