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Detection of Human Cytomegalovirus in Different Histopathological Types of Glioma in Iraqi Patients
Authors :
Haidar A. Shamran, Haider S. Kadhim, Dennis D. Taub, Robert L. Price, Mitzi Nagarkatti, Prakash S. Nagarkatti, and Udai P. Singh
Abstract
Human Cytomegalovirus (HCMV) is an endemic herpes virus that reemerges in cancer patients enhancing oncogenic potential. HCMV infection is associated with certain types of cancer morbidity such as glioblastomas. HCMV, like all other herpes viruses, has the ability to remain latent within the body of the host and can contribute in chronic inflammation. To determine the role of HCMV in glioma pathogenesis, paraffin-embedded blocks from glioma patients (
Publication Date
2015-03-19
Status
Approved