Abstract
Background Hemodialysis patients experience frequent and various cutaneous manifestations. Chronic renal failure
(CRF) is a clinical state, which results in declining of kidney functions.
Objective To evaluate the frequency and nature of cutaneous lesions associated with CRF patients on
hemodialysis.
Methods Fifty patients with chronic renal failure on hemodialysis in Al-Kadhimiya Teaching Hospital, Dialysis
Center from the period of February 2012- May 2012 were conducted in this case series study.
Results All patients included in this study had at least one cutaneous manifestation related to chronic renal
failure. The most frequent findings were pruritus (100%), pallor (100%), xerosis (100%),
hyperpigmentation (74%), petechae (40%), ecchymosis (30%) and wrinkles (30%). Nail changes were
half and half nail (76%), koilonychias (48%) and splinter hemorrhage (28%). Oral changes were
xerostomia (88%) and ulceration (52%). Other manifestation like hair changes (42%) was seen.
Conclusion Chronic renal failure is associated with various cutaneous manifestations caused by hemodialysis or the
disease itself. The most frequent findings; pruritus, pallor and xerosis. The early diagnosis of cutaneous
changes may decrease the morbidity and eventually lead to the improvement of life quality in these
patients.
Keywords Chronic renal failure, hemodialysis, cutaneous manifestations
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2013
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