Magnetic Resonance Imaging (MRI) is increasingly being used as an investigation tool in status epilepticus (SE). It
measures edema and cytotoxic edema that includes both cortical and/or subcortical constructions. The objective of our
study is to identify the brain MRI changes that occur in patients with status epilepticus. A cross can aid in understanding
ictal/postictal pathophysiology. Peri-ictal abnormalities may apparent as vasogenic -sectional analytic study conducted
on patients with status epilepticus admitted to the emergency room or neurological ward at Al–Imamain AL-Kadhymain
Medical City and AL-Yarmook Teaching Hospital for the period between January 2018 and January 2019. Brain MRI
exam was performed for eligible patients using 3 Tesla MRI unit utilizing standard imaging protocol consisting of the
following sequences: axial T2, coronal FLAIR, axial and/or sagittal T1, DWI and ADC maps with additional sequences
tailored by the available clinical data and the imaging findings. Patients with positive MRI findings attributable to status
were followed up by an MRI exam after 3 months. 28 patients were included in this study. The mean age of the patients
was 40.6±18.4 years and the age range 18-80 years. Female to male ratio was 2.1:1. The frequency of MRI changes in SE
patients was 3 out of 28 (10.7%). History of epilepsy was present among 28.6% of patients with SE. The primary
etiology of status epilepticus for patients with MRI changes were a remote ischemic stroke for one patient and idiopathic
etiology for the other two patients. Follow up MRI showed that two patients (66.7%) had reversible MRI changes, while
one patient (33.35%) had mixed reversible and irreversible changes. A significant negative association was observed
between the time interval from SE onset to MRI and the development of SE-related brain MRI changes (p=0.02). Our
results show that 10.7 % of patients with status epilepticus had positive brain MRI changes attributable to status. The
earlier an MR exam is performed for these patients, the more likely that MRI changes will be observed.
(FULL ARTICLE LINK) Read more ...
January 2020
|
|
|
