Spirometry is used as a complementary device for diagnosis of a disease; spirometry helps make a diagnosis by differentiating between obstructive lung diseases, such as asthma or chronic obstructive pulmonary disease (COPD), and restrictive lung disorders, such as interstitial pneumonia. Forced Vital Capacity (FVC) is defined as the total expiratory volume from one time of a maximally forced expiration maneuver. Forced expiratory volume in third second (FEV3) is dependable parameter most commonly studied as an alternative to FVC as they easier because the patients are not required to perform maximal end-expiration. the study aims to Evaluate the role of FEV3 and FEV1/FEV3 as alternative for FVC and FEV1/FVC in spirometric evaluation of patients with chronic obstructive airway diseases. Cross- sectional, case- control ,comparative study. 80 patients with chronic obstructive airway diseases and (160) apparently healthy subjects underwent spirometric test. FVC measured and compared with FEV3 in both groups. The results show that there was significant difference (p< 0.05) between patients and control regarding all spirometric parameters and all parameters were higher in control than patients. Females were more common than males. There was significant difference between patients and control regarding FEV1%, FVC% & FEV3% for all age groups. There was no significant difference (p>0.05) between FVC%, FVC (L) and FEV3%, FEV3 (L) regarding all age groups. There was no significant difference (p>0.05) between FVC% and FEV3% regarding female patients and also regarding male patients. The Receiving Operating Characteristic (ROC) curve shows that the Area Under the Curve (AUC) for FEV1/FVC was(0.726±0.057), FEV1/FEV3 was (0.665±0.64) (mean ± standard error of mean). (95% confidence interval) for FEV1/FEV3 was (0.542- 0.792) and (0.614-0.839) for FEV1/FVC. In conclusion, there was no significant differences between FEV3, FEV1/FEV3 and FVC, FEV1/FVC, respectively. So, FEV3 can be used as alternative to FVC in spirometric evaluation of patients with chronic obstructive airway diseases
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2020
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