: A prospective cohort study of 50 hospitalized patients in Al-Kadhimain teaching hospital in Baghdad at January 2022 who
aged 30-80 were chosen randomly regarding their glycemic status, then categorized into diabetic, newly diabetic, prediabetic, and normoglycemic based on ADA criteria and classified according to disease severity based on NIH criteria then followed up till recovery or death. Patients with mild COVID-19, patients with type 1 diabetes mellitus (very small number of patients) were excluded. Results: Fifty patients were included in this study. All were unvaccinated and had severe disease, with a mean age of 63 years (23 females and 27 males) and a mean BMI (30 kg/m2). Of them, 19 were diabetic, 10 were newly diagnosed with diabetes, 11 were prediabetic, and 10 were normoglycemic classified based on ADA criteria. A 62% of patients were found to be hypertensive. Blood urea and the need for assisted ventilation were higher among hyperglycemic patients (P ¼ .06). The overall mortality was 32%. Mortality was higher in newly diabetic 50%, 37% diabetic, 36% in prediabetic and zero in normoglycemic (P ¼ .06). There was no significant difference in inflammatory markers and serum creatinine elevation among different patient groups.
Discussion/Conclusion: The relatively small size sample is due to single-center study because of unavailability of HbA1c and some inflammatory markers in other infectious wards in field hospitals for COVID-19. The interrupted availability of HbA1c in our hospital. The need for assisted ventilation and mortality rate was higher in newly diagnosed DM and equal in prediabetic patients despite the higher level of HbA1c and RBS in diabetic patients; this was mostly due to control of other risk factors like hypertension and the use of statins. Most severe cases of covid are among old age, unvaccinated, overweight to obese, hypertensive, and hyperglycemic patients. Nineteen cases were diabetic, 10 were newly diagnosed with diabetes, 11 were prediabetic, and 10 were normoglycemic. Blood urea and the need for assisted ventilation were higher in newly diagnosed DM, diabetic, and prediabetic patients. Mortality was higher in newly diabetic, diabetic, prediabetic, and zero in normoglycemic patients.
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2023
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