Evaluation of High Sensitive C-Reactive Protein in Relation With Dyslipidemia in Patients With Subclinical Hypothyroidism
محمود شاكر خضير
Authors : Mahmood Shakir Khudhair, Mohammed Al-Shammary
Subclinical hypothyroidism is a common health problem when compared with overt hypothyroidism, with an incidence of 3% to 8%, both associated with an increased cardiovascular risk. The aim of the study is to determine the association between high sensitive C-reactive protein and subclinical hypothyroidism in comparison with controlled patients with hypothyroidism under treatment, and also investigate the association between high sensitive C-reactive protein and dyslipidemia in subclinical hypothyroidism. This is a cross sectional study. Forty patients were selected for the study, which included 20 cases of subclinical hypothyroidism and 20 cases of overt hypothyroidism patients under replacement therapy. Thyroid functions test, lipid profile, and high sensitive C reactive levels were performed on venous blood samples. Results: In the present study,mean high sensitive C-reactive protein was significantly higher in the subclinical hypothyroidism patients compared with control patients (2.7 ± 2.0 vs 1.1 ± 1.1, P ¼.004). This study suggests that patients with subclinical hypothyroidism have increased inflammatory markers (high sensitive C-reactive protein) along with dyslipidemia that increase the future risk of further development of cardiovascular disorder

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