Background:At least in 25% of infertile men, no identifiable cause can be attributed
to the problem,so it is termed idiopathic infertility. Those men are candidates
for empiric medical therapy which include antioxidant therapy. Men upplement
Plus (MFS Plus) uses a powerful all-natural formula of many antioxidants
in addition to Relora to improve semen quality.
Objectives:To evaluate the effect of MFS Plus on sperms concentration, motility
and morphology in men with oligo and/or asthenozoopermia in sample of Iraqi
infertile males.
Methods:Acomparative clinical trial study was conducted at High Institute of
Infertility Diagnosis and Assisted Reproductive Technologies during the period
from July 2015 till February 2017. Male partner of infertile couples who had one
or more of the following criteria oligo, astheno, and/or teratozospermia according
to criteria of WHO 2010 were involved in this study.
Eighty-one males were divided randomly into two groups, the first group (group
A) were given MFS Plus capsule AMS® (America Medic & Science) two capsules
twice daily for three months and the second group (group B) were given
vitamin E capsule (one capsule three times daily) for the same period.A second
semen analysis were done after three months for each subject in both groups to
show the effect of both types of treatment on semen quality.
Results:There was a highly significant increase in sperms progressive motility %
(14.0±11.41 vs 29.35±15.61, p value < 0.001) and a highly significant decrease
in immotile sperms % (60.15±19.3 vs 41.52±18.18, p value < 0.001) in the group
of patients who received MFS Plus treatment. Moreover, there was significant
increase in sperm concentration and percentage of normal sperm morphology (p
value = 0.027, 0.019 respectively). However, no significant change was observed
regarding semen volume and percentage of non-progressive motility.Whereas
there were no significant changes in any of semen analysis parameters in the
group of patients (group B) who received placebo.
Conclusion:MFS Plus usage for three months is very beneficial for sperm motility
in addition to its valuable effect on sperm concentration and morphology and
it is more efficient than vitamin E alone.
Keywords:male infertility, sperm motility, antioxidants, MFS plus, vitamin
E.
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2018
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