Abstract: The aim of this review is to examine all urethral strictures and stenoses subsequent to treatment
for prostate cancer, including radical prostatectomy (RP), radiotherapy, high intensity focused ultrasound
(HIFU) and cryotherapy. The overall majority respond to endoscopic treatment, including dilatation,
direct visual internal urethrotomy (DVIU) or bladder neck incision (BNI). There are adjunct treatments
to endoscopic management, including injections of corticosteroids and mitomycin C (MMC) and urethral
stents, which remain controversial and are not currently mainstay of treatment. Recalcitrant strictures are
most commonly managed with urethroplasty, while recalcitrant stenosis is relatively rare yet almost always
associated with bothersome urinary incontinence, requiring bladder neck reconstruction and subsequent
artificial urinary sphincter (AUS) implantation, or urinary diversion for the devastated outlet.
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2017
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