The Wild cherry, Sweet cherry (botanic name, Prunus avium) is a species of cherry fruits which has wide distribution in the world. To
evaluate the efficacy of using global medium alone versus global medium plus alcohol extract of Prunus avium for in vitro sperm
activation (ISA) to asthenozoospermic human semen samples to improve sperm parameters. The study was done on thirty five
asthenozoospermic human semen samples. The semen parameters were recorded according to WHO criteria (1999). All semen
samples were undergone activation, by using Global medium alone as control group, and by using a mixture of global medium with
ethanol extract of Prunus avium to be considered as an experimental group. The results were recorded 30 minutes and 60 minutes
after incubation. The results of this study showed significant difference (P˂0.05) in percentage of sperm moƟlity, grade A, grade B
and percentage of normal sperm morphology of post activation with Global medium compared with pre-activation results of semen
samples, there were significant difference (P˂0.05) in these results between the experimental group and control group 30 and 60
minutes after activation. Mixing of alcohol extract of Prunus avium with sperm activation media has enhancing effect on sperm
parameters.
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Int J Pharm Sci Rev Res 2014; 25(1):65-68.
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