Preeclampsia (PE) is characterized by endothelial dysfunction with vasoconstriction due to cell adhesion molecules or mediators released by defective placentation. Platelet selectin (P-selectin) and epithelial cadherin (E-cadherin) are the cell adhesion molecules, is elevated in many inflammatory conditions including PE.
Objective
To investigate if P-selectin and E-cadherin levels can be used as a marker for adverse outcomes in pregnancy complicated with PE.
Patients and Method
This study involved 90 pregnant women in their third trimester of pregnancy divided into2 group: Group A: involves 45 pregnant women with PE.
Group B
involve 45 healthy pregnant women and normal fetal growth (Control group).
Result
The results show there were a high significant increase in the mean values of P-selectin with high increase in the mean values of E-cadherin in PE group when compared to control group. ROC curve …
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2020/1/1
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