Undergraduate studies - Department of Pathology & Forensic Medicine
Undergraduate studies - Department of Pathology & Forensic Medicine
Third year curriculum (PATPat-31) First semester (5.5 credits) 60 hours theory (4 hours/week) 90 hours practical (3 hours/week) (1) Theory
1. Introduction to pathology
Course objectives: At the end of the course the student should be able to describe basic concepts of pathology and pathogenesis and to list causes of disease.
- Definitions of pathology, pathogenesis and etiology
- Basic concepts of etiology or cause of disease
- Pathogenesis
- Morphologic changes
- Functional derangement and clinical manifestation
2. Cellular adaptation, cell injury and death
Course objectives: At the end of the course the student should be able to describe major concepts of reversible and irreversible cell injury and to discriminate between necrosis and apoptosis.
- Cellular Responses to Stress and Noxious Stimuli
- Cellular Adaptations of Growth and Differentiation
- Cell Injury and Cell Death
- Causes of Cell Injury
- Mechanisms of Cell Injury
- Reversible and Irreversible Cell Injury
- Morphology of Cell Injury and Necrosis
- Examples of Cell Injury and Necrosis
- Apoptosis
3. Degeneration and deposits
Course objectives: At the end of the course the student should be able to define setiatosis, hyaline changes, calcification and hemochromatosis.
- Intracellular Accumulations
- Steatosis (Fatty Change)
- hyaline change
- pigments
- Pathologic Calcification
- Hemochromatosis and hemosiderosis
4. Acute and chronic inflammation
Course objectives: At the end of the course the student should be able to describe mechanism of acute inflammation, to list causes of inflammation, to define granuloma, and to list causes of granulomatous inflammation.
- General Features of Inflammation
- Acute Inflammation
- Chemical Mediators of Inflammation
- Outcomes of Acute Inflammation
- Morphologic Patterns of Acute Inflammation
- Chronic Inflammation
- Granulomatous inflammation
- Systemic Effects of Inflammation
- Consequences of Defective or Excessive Inflammation
5. Tissue Renewal and Repair
Course objectives: At the end of the course the student should be able to define tissue renewal and repair, to describe scar formation and fibrosis.
- Definitions
- Control of Normal Cell Proliferation and Tissue Growth
- Mechanisms of Tissue Regeneration
- Extracellular Matrix (ECM) and Cell-Matrix Interactions
- Repair by Healing, Scar Formation, and Fibrosis
- Cutaneous Wound Healing
- Fibrosis
- Overview of Repair Responses After Injury and Inflammation
6. Hemodynamic Disorders
Course objectives: At the end of the course the student should be able to define edema to list causes of edema, to describe congestion, to define shock and to list causes of shock.
- Edema and heart failure
- Hyperemia and Congestion
- Hemorrhage
- Hemostasis and Thrombosis
- Shock
7. Genetic Disorders
Course objectives: At the end of the course the student should be able to define mutation, to be familiar with patterns of genetic disorders and to know the concept of molecular diagnosis.
- Mutations
- Mendelian Disorders
- Disorders with Multifactorial Inheritance
- Cytogenetic Disorders
- Single-Gene Disorders with Nonclassic Inheritance
- Molecular Diagnosis
- Diagnosis of Genetic Diseases
8. Immune pathology
Course objectives: At the end of the course the student should be able to describe types of hypersensitivity reaction, to define transplant rejection, to define autoimmune disease and describe types of Immunologic deficiency.
- Mechanisms of hypersensitivity reactions
- Transplant rejection
- Autoimmune diseases
- Immunologic tolerance
- Immunologic deficiency syndromes
9. Neoplasia
Course objectives: At the end of the course the student should be able to define neoplasia, to name different tumors, to differentiate between benign and malignant neoplasms and to know basic concepts of molecular basis of cancer.
- Definitions
- Nomenclature
- Biology of Tumor Growth: Benign and Malignant Neoplasms
- Molecular Basis of Cancer
- Carcinogenic Agents and Their Cellular Interactions
- Host Defense against Tumors—Tumor Immunity
- Clinical Features of Tumors
10. Infectious diseases
Course objectives: At the end of the course the student should be able to describe general principles of microbial infections and to be familiar with major viral, bacterial, fungal and parasitic infections.
- General Principles of Microbial Pathogenesis
- Viral Infections
- Bacterial Infections
- Fungal Infections
- Parasitic Infections
11. Environmental and Nutritional Pathology
Course objectives: At the end of the course the student should be able to describe relation between environmental exposures and disease, to be familiar with effects of smoking and alcoholism and to be familiar with under nutrition and obesity.
- Environment and Disease
- Common Environmental and Occupational Exposures
- Tobacco Use
- Alcohol Abuse
- Nutrition and disease: nutritional deficiencies, obesity
12. Hematology
Course objectives: At the end of the course the student should be able to be familiar with diseases originating from RBC, WBC and platelet disorders, to describe basic concepts of coagulation disorders and to list indications and complications of blood transfusion.
- Anemia
- Acute leukemia
- Chronic leukemia
- Multiple myeloma
- Coagulation disorders
- Blood Transfusion
13. Cardiovascular system
Course objectives: At the end of the course the student should be able to describe major congenital heart disease, to be familiar with ischemic heart disease and to basic concepts of myocardial and pericardial disorders.
- Congenital Heart Disease
- Ischemic Heart Disease
- Hypertensive Heart Disease
- Valvular Heart Disease
- Cardiomyopathies
- Pericardial Disease
- Tumors of the Heart
14. Respiratory system
Course objectives: At the end of the course the student should be able to describe major types of pneumonia, to discriminate between obstructive and restrictive pulmonary diseases and to be familiar with broncogenic carcinoma.
- Pulmonary Infections
- Obstructive Pulmonary Diseases
- Restrictive Pulmonary Diseases
- Diffuse Interstitial (Infiltrative, Restrictive) Diseases
- Tumors
Third year Practical curriculum (PATPat-P1) First semester
1. Introduction to pathology
Course objectives: At the end of the course the student should be able to describe basic concepts of pathology and pathogenesis and to describe method of handling biopsy and cytology specimens.
- Definitions of pathology, pathogenesis and etiology.
- Definition of biopsy and techniques.
- Cytopathology technique.
2. Acute inflammation
Course objectives: At the end of the course the student should be able to describe basic vascular and cellular changes of acute inflammation.
- Acute appendicitis: causes, pathogenesis, gross and microscopic features and complications.
3. Chronic inflammation
Course objectives: At the end of the course the student should be able to describe basic histologic changes of chronic inflammation.
- Nasal polyp: causes, pathogenesis, gross and microscopic features and complications.
- Chronic cystitis: causes, pathogenesis, gross and microscopic features and complications.
- Chronic cholycystitis: causes, pathogenesis, gross and microscopic features and complications.
4. Chronic granulomatous inflammation
Course objectives: At the end of the course the student should be able to describe basic histologic changes of chronic granulomatous inflammation.
- T.B lymphadenitis: causes, pathogenesis, gross and microscopic features and complications.
- Foreign body granuloma: causes, pathogenesis, gross and microscopic features and complications.