On Sunday, March 17, 2024, student Zahraa Yahya Hanoun from the Department of Human Anatomy successfully defended her Master's thesis entitled: **E-cadherin Level and Immunohistochemical Expression for Assessment of Ovarian Reserve in Rabbits** The study aimed to evaluate the level of E-cadherin and its immunohistochemical expression as a predictor of ovarian reserve. The results of the current study showed significant differences between the right ovaries of group B (younger age) and group C (older age), with elevated levels of plasma E-cadherin and immunohistochemical expression, and a higher number of primordial follicles in group B compared to group C. The number of antral follicles in group C was higher than in group B. However, there was no significant difference in ovarian weight. Comparisons between the left ovaries of group B and group C also showed significant differences, with elevated plasma E-cadherin levels, higher immunohistochemical expression, and a greater number of primordial follicles in group B compared to group C. The number of antral follicles was higher in group C compared to group B, along with ovarian weight. The results also indicated that the number of primordial and primary follicles in group B was higher than in group C, while the number of secondary and antral follicles in group C was higher than in group B. In group B, there were no statistically significant differences between the right and left ovaries in plasma E-cadherin level, immunohistochemical expression of E-cadherin, and the number of primordial follicles. In group C, there was also no significant difference between the right and left ovaries in plasma E-cadherin level, immunohistochemical expression of E-cadherin, and the number of primordial follicles. Significant differences were found in plasma E-cadherin levels among rabbits in group A (males), group B (young females), and group C (older females). Additionally, significant differences in plasma E-cadherin levels were observed between rabbits in group A and group B, and between group A and group C. The study concluded that higher levels and immunohistochemical expression of E-cadherin correlate with an increased number of primordial follicles and that E-cadherin levels decrease with advancing age. The defense committee was composed of: - Prof. Dr. Haider Abdul Rasul Jafar (Chairman) - Assoc. Prof. Dr. Ali Ibrahim Rahim (Member) - Assoc. Prof. Dr. Huda Rashid Karim (Member) - Prof. Dr. Thair Mahmood Farhan (Supervisor) The thesis was successfully accepted with a grade of Excellent.
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