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| Department of Chemistry and Biochemistry |
| The chemistry and biochemistry branch was established in 1987. The branch is to supervise graduate studies since 1993where the first Master degree was granted in1995, and the branch is still ongoing to grant professional high diploma, Master and doctoral degrees in clinical biochemistry and medical chemistry. The branch also is to teach different subjects to graduate students (Master and Doctoral Degrees) in the other college branches.
A number of the branch professors participate in Iraqi Board exams and various assessment committees, and in discussion of graduate and board students’ research to evaluate research for publication in scientific journals inside and outside Iraq, and assessment of graduate students’ theses. Also the branch had a distinct role by giving different scientific consultations to the clinical chemistry laboratory of Al-Imamain Al-kathimain hospital.
The branch has a distinct participation with the Continuous Education Unit in the college by holding various courses and seminars on topics related to the definition of the dangers of toxic chemical substances as well as to modern technologies used in clinical diagnosis fields. Also, a number of our teaching staff members has participation in conferences and seminars inside and outside the college. The branch has a patent granted to Prof. Dr. Muhammad Omran Hamza in 2021 and for Prof. Dr. Istabraq Abd al-Rasul al-Wasiti in 2022.
In addition to that, our branch has an active contribution with the medical research centre through correlating staff members continuously. Besides, the branch has important role in the health centre of the college by participation of many professors in the daily presence in the centre.
Moreover, we have active participations as a membership in different ministerial committees such as the Scientific Committee of the Iraqi Association/Emergency Medicine ( Ministry of Health) and the Iraqi Board of cancer (Ministry of Health) and the committee to follow -up the final exams (Ministry of Higher Education and Scientific Research) and many other ministerial committees.
A number of the branch professors, and as a result of their ongoing efforts and fruitful liberality, gained letters of thanks from the ministers, the university president and the college deans.
The teaching staff has an active role and contribution to the research work about problems of health and environment situation in Iraqi society. Many of our professors publish a number of concrete researches in international fields with a relatively high impact coefficient in reliable magazines inside and outside Iraq. Also many of the branch professors participated in the teaching staff development courses through traveling abroad and acquiring additional international expertise and occupational safety and emergency medicine courses. The branch has also an active participation in the editorial staff of the Iraqi journal of medical sciences through contribution to the editorial staff and in the educational guidance unit as well by meeting students and solving their problems, and also in quality and reliability committees.
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| The PhD defense of Hisham Ahmed Shaker in the Department of Chemistry and Biochemistry. |
A PhD dissertation defense session was held on Tuesday, July 23, 2024, at 9:00 AM in the discussion hall of the Department of Chemistry and Biochemistry/Medical Biochemistry, for PhD student Hisham Ahmed Shaker. His dissertation is titled:
"Evaluation of nuclear factor kappa B, its inhibitor kinase subunit beta and interleukin-1 receptor associated kinase as additional serum diagnostic biomarkers for women with Poly Cystic Ovary Syndrome." The defense committee was composed of:
- Prof. Istabraq Abdul Rasool Kwairy ..... Chair
- Prof. Hala Abdul Qadir Abdul Latif .... Member
- Prof. Alaa Hussein Jawad ........... Member
- Prof. Hind Shaker Ahmed ....... Member
- Assoc. Prof. Hassan Hussein Taha ..... Member
- Prof. Ria Suleiman Baban ...... Member and Supervisor
- Prof. Enas Adnan Abdul Rasool ....... Member and Supervisor
The dissertation was accepted successfully with a grade of "Excellent."
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| **Ph.D. Candidate (Raghda Adnan Siyabakhsh) Defense** |
On Thursday, July 18, 2024, Ph.D. candidate (Raghda Adnan Siyabakhsh) successfully defended her dissertation at 9:00 AM in the discussion hall of the Department of Chemistry and Biochemistry / Medical Biochemistry, entitled:
**Evaluation of Proline, Epiregulin Levels and Prolidase Enzyme Activity in Comparison with Cancer Antigen 15-3 (CA 15-3) as Potential Biomarkers in Female Breast Tumours**
### Objective of the Study:
The study aims to evaluate the role of proline, epiregulin, and prolidase in diagnosing patients with benign and malignant tumors compared to the cancer antigen CA 15-3 through the following objectives:
1. Determine the levels of prolidase enzyme activity, in addition to proline and epiregulin levels, in the serum of women with benign and malignant breast tumors (before and after surgery for malignant tumors).
2. Investigate the relationship between prolidase enzyme activity levels, proline, and epiregulin with cancer antigen CA 15-3 levels before and one month after breast cancer surgery.
### Results:
The current study showed:
A- Women with benign breast tumors exhibited higher levels of proline compared to women with breast cancer, and the difference was significant. Conversely, the average serum level of epiregulin in breast cancer patients was significantly higher than in women with benign breast tumors. Similarly, women with breast cancer showed higher levels of carbohydrate antigen 15-3 and prolidase activity compared to women with benign breast tumors, with a significant difference.
B- The serum level of proline increased after surgery with an average difference (before and after surgery) of 7.2 ± 2.96 pg/ml, showing a significant difference. On the contrary, the serum level of carbohydrate antigen 15-3 decreased with a notable difference of 12.97 ± 8.73 pg/ml, which was highly significant.
Despite the significant post-operative decreases in both epiregulin and prolidase activity, the differences were not substantial.
### Examination Committee:
The discussion committee consisted of:
- Prof. Dr. Ria Suleiman Baban (Chair)
- Prof. Dr. Hala Ghazi Mahmoud (Member)
- Prof. Dr. Sajid Hamid Al-Halfi (Member)
- Prof. Dr. Rafal Shakib Abdul Wahab (Member)
- Assist. Prof. Dr. Ibrahim Abdullah Mahmoud (Member)
- Prof. Dr. Raed Jassim Mohammed (Member and Supervisor)
- Assist. Prof. Dr. Qahtan Adnan Mahdi (Member and Supervisor)
The dissertation was accepted successfully with distinction.
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