On Sunday, August 18, 2024, Master’s student Shaima Ali Hussein from the Department of Pharmacology defended her thesis titled: **"Effects of Scutellarin and Doxofylline on Cyclophosphamide-Induced Infertility in Male Rats"** The study aimed to evaluate the protective and therapeutic effects of Scutellarin and Doxofylline on the testes of male rats exposed to a single dose of Cyclophosphamide. The research assessed the Gonadosomatic Index (GSI), sperm parameters (motility, concentration, and viability), levels of sex hormones (LH, FSH, Testosterone), and oxidative stress markers (MDA, AOPP, GPx) in testicular tissues. Key findings included: - Significant improvements in GSI (P<0.05) and sperm parameters (motility, concentration, viability) (P<0.05) with the use of Scutellarin and Doxofylline. - Increased testosterone levels and decreased LH and FSH levels (P=0.002). - Enhanced oxidative stress markers with decreased MDA and AOPP levels and increased GPx enzyme activity in comparison to the Cyclophosphamide group. - Histological analysis revealed notable changes in the testicular structure, such as damage to seminiferous tubules and a reduced Johnson score with Cyclophosphamide. However, Scutellarin and Doxofylline significantly restored the testicular structure (P=0.001). The study supports that Scutellarin, Doxofylline, and their combinations, at the doses used, effectively mitigated the toxicity in the testes of male rats induced by Cyclophosphamide, likely due to the antioxidant properties of the drugs. The examination committee consisted of: - Prof. Dr. Ahmed Rahma Ali (Chair) - Prof. Dr. Inas Jawad Kazem (Member) - Asst. Prof. Dr. Raed Jasem Mohammed (Member) - Asst. Prof. Dr. Fouad Kazem Katah (Member and Supervisor) The thesis was accepted with honors. 
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