On Wednesday, August 28, 2024, the Master's thesis of student Mohammed Hassan Kazem from the Department of Physiology and Medical Physics was discussed. His thesis was titled: **"Hypofractionated Gamma Knife Radiosurgery in Big Tumors"** **Objective:** The study aimed to determine the most effective dose to achieve better results without the need for surgery. Additionally, it sought to regulate the progression of benign and malignant tumors to reduce their size. **Conclusion:** The study revealed treatment plans using Gamma Knife radiosurgery for different types of tumors, with metastases being the most common. The highest dose was found in metastases, followed by meningiomas, gliomas, acoustic neuromas, and arteriovenous malformations. After six months, the treatment showed a significant reduction in tumor size, with meningiomas showing the highest reduction. Fibrosis around the tumor was observed, and a positive response to radiotherapy was noted. Hypofractionated Gamma Knife radiosurgery is superior in avoiding damage to healthy tissues while still delivering the required dose to large or complex brain lesions. **The discussion committee consisted of:** - Prof. Dr. Nada Fadel Tawfiq (Chair) - Prof. Dr. Amal Hussein Abbas (Member) - Prof. Dr. Abdul Amir Jassim Mohammed (Member) - Prof. Dr. Rasha Subaih Ahmed (Supervisor) - Prof. Dr. Yasser Mohammed Hassan Hamandi (Supervisor) The thesis was successfully accepted with distinction. 
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